Buprenorphine Remains One Of The Most Effective Drugs For The Treatment Of Acute Pain, Chronic Pain, And Addiction

 

Buprenorphine is a powerful, long-acting opiate drug. It can alleviate the pain of post-traumatic stress disorder, also known as PTSD, and other serious psychological and physical disorders. Buprenorphine not only is not usually used as an opiate pain pill. Buprenorphine can also be used for non-opiate purposes not specifically listed in this drug guide. Buprenorphine belongs to a family of long-acting opioid agonists or narcotics. It creates its effects by exerting opiate actions on the opioid receptors in the brain. The majority of its derivatives are readily absorbed into the bloodstream. However, it can be metabolized and then released through the actions of opioid receptors in the GI tract and liver. This is why it is primarily used as an injection in medical emergencies, where it is quick-acting, has little or no tolerance, and is highly efficient.

Buprenorphine works as an opioid agonist by causing rapid and sustained dilatation of the pupil's pupils during rapid eye movement (REMS) in patients who have taken the medication in conjunction with alcohol or benzodiazepines. Due to its fast action in the GI tract, Buprenorphine cannot be habit-forming, as it requires to be taken continuously over a long period of time. This characteristic allows it to be used as an addition to conventional pain management in the treatment of refractory conditions such as asthma and COPD, which are caused by constant obstruction of the respiratory tract.

The most common side effects of Buprenorphine are constipation, which may result from insufficient bowel elimination, and increased urge to urinate. In addition, a patient experiencing any of the following should not take Buprenorphine: narcotics, alcohol, heroin, hydrocodone, propoxurics, methadone, oxycodone, and tramadol. In the recent past, the U.S. Food and Drug Administration (FDA) approved Cassipa (buprenorphine and naloxone) sublingual film (applied under the tongue) for the maintenance treatment of opioid dependence.