Blood Clotting Factors, Various Types, Effects, and Their Link with Deep Vein Thrombosis

 

Blood Clotting Factors

The term thrombosis refers to the condition that a blood clotting factor molecule clogs up the blood vessels. Thrombosis is a complex biological process involving the blood vessel wall, calcium, and iron. Blood clotting factors have complex conformations that involve the proteins UL and VL. These clotting factors also interact with several other molecules that are involved in blood clotting such as fibrin. If a blood clotting factor molecule or a proenzyme collides with a fibrin molecule it can stop bleeding.

High prevalence of deep vein thrombosis is expected to boost demand for blood clotting factors. According to the Centers for Disease Control and Prevention (CDC), from 1998 to 2014, around 900,000 people suffer from deep vein thrombosis (DVT)/ pulmonary embolism each year in the U.S.

There are several known blood clotting factors and there are several known risk factors for developing thrombosis. Risk factors for developing thrombosis include: hereditary clotting factors, hemorrhage, surgery, liver disease, obesity, chronic venous insufficiency (or DI), and poor circulation. Some people develop thrombosis due to factors associated with more commonly occurring diseases such as those involving the kidneys, gallbladder, liver, and pancreas. People with hemophilia are commonly affected by thrombosis due to the deficiency of the factor viii, a protein needed for clotting. In addition, thrombosis is most common in people with a history of spontaneous bleeding.

A combination of factor viii and proenzyme Q10 has been shown to be very effective in stopping the bleeding effect of thrombosis. Blood clotting factors that do not produce any adverse side effects are considered fairly safe, and are often recommended. As a matter of fact, there are currently a variety of dietary supplements that are presently available to assist individuals who suffer from hemophilia to stop bleeding. However, these products can only be purchased by individuals who suffer from hemophilia and are within the age of 18 years.

Comments