Development of New Bone Regeneration Technologies and High Prevalence of Orthopedic Diseases to Boost Demand For Bone Regeneration Material
In recent years, there has been an increased interest in using bioactive glass for bone regeneration. Bone regeneration is a promising treatment for spinal injuries due to high prevalence of diseases such as osteoarthritis, rheumatoid arthritis, and spinal stenosis. According to the study ‘Osteoarthritis in Europe: Impact on health status, work productivity and use of pharmacotherapies in five European countries’ that examined the impact of peripheral joint osteoarthritis across five European countries, U.K (43.6%), France, (25.6%), Germany, (15.2%), Spain, (8.4%), and Italy (7.1%) recorded high prevalence of peripheral joint osteoarthritis, with majority of cases aging 55-74 years.
Boneregeneration materials that contain bioactive chemicals are now being
researched for their ability to promote the growth of new cells within bones.
Such studies have revealed that calcium phosphate and calcium sulfates are two
of the bioactive substances that can play a key role in bone regeneration. Studies
have also shown that adding bioactive glass to spinal implant surgeries
resulted in significant improvements in bone growth. The increase in bone
density was found to be permanent. This means that after the addition of the
substances, postoperative bone growth was found to be sustained for the long
term. Moreover, there were no reports of adverse side effects. Therefore, the
scope of this special issue of bone regeneration materials has therefore been
expanded to include the recent findings relating to the potential to add
bioactive ingredients to the surgical wounds used in the treatment of bone
injuries.
Calcium
phosphate is used as an active ingredient in topical solutions and as a bone
regeneration material. There have also been increased research activities in the
fields of osteoporosis and vitamin D deficiency in relation to bone formation
and regeneration. As more attention is paid to prevention and delay the effects
of osteoporosis, there is an increased need to understand the role of vitamin D
and its importance in the bone regeneration process. It is here that the
potential benefits of vitamin D supplementation can be best realized through
increased research activities.
Development
of new bone regeneration technologies is expected to boost demand for bone regeneration
materials. For instance, in February 2021, Osteopore International, an implant
manufacturer, in collaboration with Maastricht University Medical Center,
developed a bioresorbable 3D printed cage to help patients regenerate new bone
cells.
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