Demand for Life Cell Imaging Is Increasing with the Increasing Incidence of Cancer
The life cell imaging is the investigation of live cells with time-lapse microscope. It is used by many researchers to obtain an understanding of specific biological function via the study of rapidly changing cellular dynamics. Live cell imaging was first pioneered in the first decade of the 20th century. The principle of imaging through living cells has evolved over the past decades. Originally it was achieved through electron microscopy, where the cells were fixed on a slide and a fluorescent dye was attached. Images would then be taken as the cells were engulfed in culture. The technique was refined later with the introduction of nuclear medicine and focused on the blood where cells could be examined for cancer markers.
Life cell imaging is gaining significant traction due to
increasing techniques in various fields such as electro physiology, drug
discovery, oncology, developmental biology, neurobiology, cell biology, and
stem cell biology. Moreover, life cell imaging helps provide insights into
dynamic processes in cell function and living cells with the help of
multicolored probes and green fluorescent protein that label molecules and
probe its function directly in live cells by light microscopy.
There are several technologies that have been applied for
imaging. Fluorescence imaging uses fluorescent proteins as probes. Optical
imaging uses light to pass through a cell or probe. Electrophoresis technique
uses electric currents to identify active proteins. Some cancers can show up as
spots where cells grow abnormally. These spots can be highly irregular and can
occur in different areas of the body. This method has also been applied for
testing new drugs. Other uses of this imaging method includes studying the
effects of transplant on human cells in culture. This technology is used for pre
and post-surgery treatments.
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