Use of Proton Pump Inhibitors Once Or Twice Daily Significantly Increases Risk of Covid-19
Protonpump inhibitors are a group of drugs whose primary function is an intense and prolonged reduction of gastric acid production. Within this category of drugs, there is currently no evidence that one chemical is more effective than the other. The FDA has approved the use of these inhibitors to treat the symptoms of gastroesophageal reflux disease, or GERD.
Gastroesophageal
reflux disease is an uncomfortable condition that often requires urgent
treatment; therefore, it is important to understand the different factors that
may affect the effectiveness of proton pump inhibitors in the treatment of gastroesophageal
reflux disease. Gastroesophageal reflux disease (GERD) is an irritating and
painful disorder of the digestive tract that primarily affects the throat, the
lower esophagus, the upper portion of the stomach, and the duodenum. The
majority of patients with GERD report abdominal pain and regurgitation, nausea,
vomiting, and abnormal sense of smell. The age-standardized prevalence per 100 000
population for GERD was 6906·4 for Germany, according to the study, ‘The
global, regional, and national burden of gastro-oesophageal reflux disease in
195 countries and territories, 1990–2017: a systematic analysis for the Global
Burden of Disease Study 2017’ published in March 2020.
Patients
who take proton pump inhibitors or acid suppressants to reduce the symptoms of
GERD should discuss their options with a gastroenterologist. An experienced
gastroenterologist can evaluate the severity of symptoms, determine the best
course of treatment, and recommend the use of a these inhibitors or acid
suppressant. Many patients mistakenly believe that if they take an
over-the-counter acid suppressant or proton pump inhibitor, they will be cured
of GERD.
However,
it should be noted that despite the fact that many medical experts support the
use of such medications for GERD, not all patients experience the same degree
of improvement. Some individuals even experience a worsening of their symptoms.
Recently, in July 2020, an online survey (submitted in The American Journal of
Gastroenterology) of over 53,000 people in the U.S suggested that using proton
pump inhibitors once or twice daily significantly increases the risk of COVID-19.
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